Percutaneous Umbilical Blood Sampling

Posted by Healthfitline On Wednesday, December 19, 2012
Percutaneous Umbilical Blood Sampling (PUBS) also known as cardocentesis or funicentesis is a diganostic procedure that is performed to detect fetal abnormalities and other fetal conditions during the pre-natal period. Percutaneous Umbilical Blood Sampling procedure is performed after 18 weeks of gestation and it involves the aspiration of the fetal blood from the umbilical vein by use of a fine needle, guided by a sonography or ultraound.
 
A sample of the blood is then removed for further analysis. Such as;
  • For complete blood count
  • Karyotyping - to check for genetic or chromosomal abnormalities.
  • Blood gases
  • Structural fetal abnormalities.
  • For direct Coomba test (to check for antibodies).
  • Fetal intrauterine growth retardation.
  • Infections and blood disorders like anemia.
  • To administer medications directly to the fetus or for intrauterine blood tranfusion.
 
To ensure that the blood aspirated during Percutaneous Umblical Blood Sampling procedure is the fetal blood and not maternal blood, the fetal sample blood is then submitted for Kleihauer-Betke (KB). This is a blood test that is used to measure the amount of fetal hemoglobin that have been transferred from a fetus to the mother. 
 
If the mother is Rh-negative, RHIG is given to prevent sensitization, since there is a possibility that the fetal blood may have mixed with maternal blood during the procedure. The fetus is then monitored before and after the procedure with non-stress test and ultrasound to make sure bleeding and contractions does not occur.
 
Complication of Percutaneous Umblical Blood Sampling
Possible complications associated with the Percutaneous Umblical Blood Sampling are:
  • Infection
  • Uterine contractions or cramping
  • Bleeding

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