Hepatitis A Virus Overview

Posted by Healthfitline On Wednesday, February 6, 2013
Hepatitis is a general term used to describe a liver inflammation due to destruction or changes of the liver tissues. The are two main classifications of hepatitis; the non-viral hepatitis and the viral hepatitis. The nonviral hepatitis can further be classified as toxic hepatitis and drug induced hepatitis. In this article, will be focusing on viral hepatitis.
 
Viral Hepatitis
Viral hepatitis refers to systemic inflammation of the liver, caused by a virus.  There are 5 definitive types of viral hepatitis infections; hepatitis A, hepatitis B, hepatitis C, hepatitis D and Hepatitis E. The most common types are; hepatitis A virus (HAV), hepatitis B virus (HBV) and hepatitis C virus (HCV).  Hepatits A and E are transmitted via fecal-oral route while hepatitis B, C and D share almost a similiar mode of  transmission.  
 
Hepatitis A Causes
Hepatitis A is transmitted via fecal-oral. You can get hepatitis A by eating food or drinking a drink that has been infected with the virus or through hand-to-mouth contact or by anal-oral contact.
 
Other ways to get infected with hepatitis A is through;
  • Getting into contact with an infected surfaces or an infected person.
  • Eating raw food that came into contact with sewage-contaminated water or faeces.
  • Poor personal hygiene - not washing your hand properly.
  • Eating food that have been prepared by a person who came into contact with the virus.
Hepatitis A Pathophysiology
In developed countries, hepatitis A virus (HAV) accounts for 20% to 25% of all cases and the prevalence of HAV antibodies seems to increase with age. It is more common in developing countries and people living under poor sanitation conditions. The infection typically starts when an adult or a child injects food or drink infected with the hepatitis A virus. Children may acquire the virus at school through poor hygiene and then spread it at home.
 
Once the child or an adult catches the virus, the incubation period of HAV is estimated to be in between 15 and 50 days (averaging, 28 - 30 days).  Once infected with the virus, an adult or a child is capable of transmitting the virus, since the virus can be excreted in the stool even before the onset of the symptoms.
 
Hepatitis A Symptoms
Initially, most patients are asymptomatic and even if the symptoms may be present, they are mild and they may resemble those symptoms experienced by an individual suffering from a flu, with the exception of anorexia.  
 
Hepatitis A symptoms may include; upper respiratory infection, low grade fever, loss of appetite, anorexia, nausea, vomiting, heartburn, flatulence, tiredeness and elevated aminotransferese levels. Jaundice and dark urine usually appear later on as the infection progresses. The symptoms seem to disappear with the appearance of the jaundice, usually 10 days after jaundice appearance. These symptoms are usually mild in children but they may be more severe in adult, especially during a relapse.
 
Hepatitis A Diagnostic Test
  • Upon the palpation of the liver and spleen, they are moderately enlarged.
  • Present of a few physical signs and symptoms upon patient assessment.
  • Stool testing for hepatitis A antigen.
  • Serum testing for hepatitis A antibodies but only if the patient is symptomatic.
  • Analysis of immunoglobulins to determine whether the infection is acute or past.
Hepatitis A Treatment and Management
Hepatis A virus usually heals by its own and no treatment is required, unless it becomes chronic or severe. The following are some ways in which hepatitis A is managed;
 
  • Bed rest during acute stage to fasten the healing process.
  • Nutritional support during periods of anorexia. Frequent small meals and enteral feeding if needed.
  • Patients is instructed to avoid taking alcohol during acute illness and atleast 6 months after the recovery.
  • Patient advised not to take medications or drugs that can contribute to liver problems.
Prevention of Hepatitis A
The following are preventive measures that can help in preventing the spread of hepatitis A;
  • Proper personal hygiene
  • Proper environmental and home sanitation.
  • Community health education.
  • Proper and safe practices when handling food.
  • Vaccination for people who are at risk of developing hepatitis A. Such as, frequent travellers to developing countries, illicit drug users, patients with chronic liver diseases, among others.
  • Reporting of hepatitis A viral outbreaks and vaccination to minimize the spreading of the infection into the community.
  • Avoid eating raw foods or street foods, especially during the outbreaks.

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